Table of Contents

Research Articles

1

Delivery of Entrapped Loperamide in Polysorbate 80 Coated Liposomes to Brain for its Antinociceptive Activity Through Central Opiate Receptors

I. Sarath Chandran, Pichandy Muthu Prasanna, Ram Kumar Sahu

Polysorbate 80, Liposomes, Loperamide, Blood Brain Barrier

Keywords: Blood-Brain Barrier, Liposomes, Loperamide, Polysorbate 80, Antinociceptive Activity

The delivery of drugs to the brain is often impeded by the blood-brain barrier (BBB), posing a significant challenge for therapeutic interventions targeting central nervous system (CNS) disorders. Thi...

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2

A History of Wallo Teklay Gizat Prison (1941-1974)

Gashaw Muhammed Motema

Wollo University, Department of History and Heritage Management, Dessie, Ethiopia

Keywords: Ethiopian history, political imprisonment, prison conditions, Wallo region, 20th century Ethiopia, Imperial regime, social justice

This research is a historical account of the Wallo Teklay Gizat Prison from 1941 to 1974. The years 1941 and 1974 were selected as the starting and finishing points because both of them are landmarks ...

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3

An Original Calendar System in the Heart of Europe: The Dacian Time Measurement at Sarmizegetusa

Cornel Samoila, Elena Kowalczyk

Institute of Historical Research, University of Bucharest, Romania

Keywords: Dacian calendar, Sarmizegetusa, ancient timekeeping, astronomical significance, historical linguistics

Sarmizegetusa, an ancient site of profound significance for the Dacian people and their Romanian descendants, serves as a focal point in the study of early European calendrical systems. This paper exp...

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4

The Mechanism of Information Storage in Open Systems

Yuriy Zayko

Institute of Theoretical Physics, Russia

Keywords: negentropy, bifurcation, heredity, variability, information theory

This article is devoted to the description of the mechanism of the transformation of negative entropy (negentropy) coming into the system from outside, into information by doubling bits of information...

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5

Analysis of Hypertension Early Warning Model Based on Classification of Blood Pressure

Benting Wan

Institute of Medical Research, Hypertension Study Group, China

Keywords: Hypertension, Early warning model, Blood pressure monitoring, Decision tree, Healthcare efficiency

There are about 160 million Chinese residents who are suffering from chronic hypertension, which requires a large number of medical personnel to provide monitoring and management services to these pat...

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6

Leishmaniasis of the Palmoplantar: A Case Report

Jamshid Ayatollahi, Ali Fattahi Bafghi, Seyed Hossein Shahcheraghi

Yazd University of Medical Sciences, Department of Dermatology, Iran

Keywords: cutaneous leishmaniasis, case report, palmoplantar lesions, tropical diseases, Iran

We report the case of a 36-year-old woman who was referred to our clinic in Yazd, Iran, with cutaneous leishmaniasis affecting the palmoplantar regions. The patient, a housekeeper, presented with a sm...

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7

Some New Classes of Ideal Convergent Multiple Sequence Spaces of Fuzzy Real Numbers

Munmun Nath, Santanu Roy

Department of Mathematics, University of Calcutta, India

Keywords: I-convergence, fuzzy real numbers, sequence spaces, metric spaces, algebraic properties

In this article, we introduce the class of I-convergent sequences of fuzzy real numbers of multiplicity greater than two. We explore various algebraic and topological properties of these spaces, such ...

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