Vol. 19, Issue 10
Section 1
ID: yNpbF
Hiroshi Yamamoto, Fatma Ozturk, Camila Alvarez
Keywords: Department of Cell Biology, Kyoto University, Japan; Molecular Biology Research Center, Istanbul University, Turkey; Department of Biochemistry, University of Buenos Aires, Argentina
Membrane trafficking is a fundamental process in cell biology that ensures proper distribution and function of cellular components. This study investigates the role of Rab GTPases in regulating endosomal membrane trafficking dynamics. Our objective was to delineate the specific contributions of Rab5...
Vol. 19, Issue 10
Section 1
ID: 5HYvK
Heiko M. Schröder, Nandini S. Verma, Takashi Umehara
Keywords: Department of Ecology, Humboldt University of Berlin, Germany; Department of Environmental Science, Indian Institute of Science, Bangalore, India; Faculty of Agriculture, Kyoto University, Japan
The resilience of grassland ecosystems is critical for maintaining ecological balance and biodiversity under changing climatic conditions. This study investigates the role of adaptive thresholds in enhancing ecosystem resilience to climatic variability. We employed a combination of field experiments...
Vol. 19, Issue 10
Section 1
ID: afSVh
Dr. Hans-Peter MĂĽller, Dr. Meera Chaturvedi, Dr. Farid Al-Mansoori
Keywords: Department of Biochemistry, University of Göttingen, Germany; Department of Systems Biology, Indian Institute of Science Education and Research, Pune, India; Department of Molecular Biology, King Saud University, Saudi Arabia
Understanding the intricate interactions within metabolic pathways across different biological kingdoms is pivotal for advancements in biotechnology and therapeutic development. This study aims to decipher the cross-kingdom metabolic communications by leveraging integrated multi-omics approaches. Ut...
Vol. 19, Issue 10
Section 1
ID: 7ZyUd
Markus J. Schneider, Li Xiaolong, Fatima Al-Zahra
Keywords: Department of Biophysics, Ludwig Maximilian University of Munich, Germany; School of Life Sciences, Peking University, China; Department of Molecular Biology, University of Tehran, Iran
Understanding the mechanisms of protein folding remains a central challenge in biophysics. This study focuses on the kinetic pathways and thermodynamic stability in the folding of small globular proteins. We aimed to elucidate the interplay between folding rates and stability by employing molecular ...
Vol. 19, Issue 10
Section 1
ID: 9LTs8
Lars J. van der Meer, Hiroshi Nakamura, Priya S. Menon
Keywords: Department of Botany, University of Amsterdam, Netherlands; Department of Plant Science, Kyoto University, Japan; Department of Plant Biotechnology, Indian Institute of Technology Madras, India
The increasing frequency of heat waves poses significant challenges to plant growth and productivity. Understanding the mechanisms of heat stress tolerance in plants is critical for developing resilient agricultural systems. This study investigates the genomic and physiological responses of Arabidop...
Vol. 19, Issue 10
Section 1
ID: ZuSvs
Lu Wei-Ming, Dieter H. Schneider, Priya Venkataraman
Keywords: Lu Wei-Ming, Department of Genetics, Peking University, China; Dieter H. Schneider, Institute of Molecular Biology, University of Heidelberg, Germany; Priya Venkataraman, Department of Biotechnology, Indian Institute of Science, India
Gene therapy has emerged as a promising approach for the treatment of monogenic disorders, leveraging advances in genome editing technologies. This study aims to evaluate the efficacy and safety of CRISPR-Cas9 mediated gene therapy in correcting genetic mutations responsible for inherited diseases. ...
Vol. 19, Issue 10
Section 1
ID: MSxvY
Andrea MĂĽller, Hiroko Matsuda, Yusuf Al-Jabari
Keywords: Department of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Department of Neuroscience, University of Tokyo, Tokyo, Japan; Department of Biomedical Sciences, American University of Beirut, Beirut, Lebanon
Neurodegenerative diseases like Alzheimer's disease (AD) are characterized by progressive synaptic loss and cognitive decline. Understanding the molecular underpinnings of synaptic vulnerability in AD is crucial for developing effective therapies. This study aimed to elucidate the proteomic changes ...
Vol. 19, Issue 10
Section 1
ID: F8Xvk
Hannes F. MĂĽller, Aditi R. Nair, Zhang Min-Jie
Keywords: Department of Molecular Biology, University of Heidelberg, Germany; Department of Biochemistry, Indian Institute of Science, Bangalore, India; RNA Research Institute, Tsinghua University, Beijing, China
The intricate process of RNA splicing is crucial for the generation of mature messenger RNA (mRNA), yet the influence of small nuclear RNA (snRNA) modifications on splicing efficiency remains poorly understood. This study aims to explore the impact of specific chemical modifications of snRNA on the ...
Vol. 19, Issue 10
Section 1
ID: xId3D
Ok-Hwa Kang, Nam-Won Kwak, Yun-Soo Seo, Tian Zhou, Ryong Kong, Sang-A Kim, Dong-Won Shin, Dong-Yeul Kwon
Keywords: Chonbuk National University, Department of Oriental Medicine, South Korea
Objective: Curcumin [1,7-bis-(4-hydroxy-3-methoxyphenyl-1,6-hepatadiene-3,5-dione], the active component of turmeric, is a polyphenolic phytochemical with anti-tumor, anti-inflammatory, anti-oxidative, and anti-allergic properties. To ascertain the molecular mechanism involved in the anti-inflammato...
Vol. 19, Issue 10
Section 1
ID: uc8aN
Sangita Saha, Santanu Roy
Keywords: Department of Mathematics, University of Calcutta, India
In this article, using an Orlicz function, some new classes of zweier I-convergent triple sequence spaces of fuzzy numbers are introduced. An effort is made to study some basic algebraic and topological properties of these introduced sequence spaces. Moreover, some inclusion relations between these ...
Vol. 19, Issue 10
Section 1
ID: L7Rn7
Alaa H. Al-Darraji, Yesra S. Abd-Al-Saheeb, Zadoon J. Kadhem
Keywords: University of Al-Maghreb, Department of Chemistry, Al-Maghreb; Missan University, Department of Medical Sciences, Iraq
Gallstones disease, or cholelithiasis, is a prevalent condition worldwide, with significant morbidity and mortality, particularly in regions like Al-Maghreb. This study investigates the unusual occurrence of gallstones in newborns in Missan city, aiming to elucidate the underlying causes and explore...
Vol. 19, Issue 10
Section 1
ID: jgM4z
Miguel Alberto González González
Keywords: Dialogues of Knowledge Research Group, University of Antioquia, Colombia
The present text is part of an investigation development that takes place between 2015 and 2016, where there’s an interest in knowing what the diversity-homogenizations, inclusions-exclusions in Colombian education are. Colombia is a country which is based on ethnic, environmental, and cultural di...
Vol. 19, Issue 10
Section 1
ID: z78K7
Claudia Reyes-Quilodran
Keywords: University of Chile, Department of Sociology, Chile
During the late 1960s and early 1970s, most Latin American countries experienced military coups and military interventions in government affairs. In Chile, the military coup of 1973 established a military regime that lasted seventeen years, from 1973 to 1990. As a result of the military dictatorship...
Vol. 19, Issue 10
Section 1
ID: Cyu1C
Chu-Ching Wang, Hsiu-Chen Chuang, Li-Ren Yang, Yu-Min Wang, Hsu-Shih Shih
Keywords: National Taiwan University, Department of Business Administration, Taiwan
Conceptualizing implementation of cloud platform in the new product development (NPD) context is still rudimentary. The primary objective of this study was to evaluate how customer relationship management (CRM) can enable innovation capabilities and then improve the performance of NPD by implementin...
Vol. 19, Issue 10
Section 1
ID: wpTHR
Peter KusĂ˝
Keywords: Department of Music Therapy, University of Bratislava, Slovakia
The purpose of this paper is to explore the integration of music therapy within the framework of Integrated Psychotherapy/Knobloch. A central component is the Interpersonal Hypothesis of Music, predicated on the idea that music inherently reflects interpersonal tendencies discernible by an independe...