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Found 7 articles for "Department of Molecular Biology"
DNA repair is a critical process that maintains genomic stability and protects against carcinogenesis. The modulation of homologous recombination (HR) pathways has shown promise in enhancing DNA repair fidelity. This study aims to elucidate the role ...
Understanding the intricate interactions within metabolic pathways across different biological kingdoms is pivotal for advancements in biotechnology and therapeutic development. This study aims to decipher the cross-kingdom metabolic communications b...
Understanding the mechanisms of protein folding remains a central challenge in biophysics. This study focuses on the kinetic pathways and thermodynamic stability in the folding of small globular proteins. We aimed to elucidate the interplay between f...
The intricate process of RNA splicing is crucial for the generation of mature messenger RNA (mRNA), yet the influence of small nuclear RNA (snRNA) modifications on splicing efficiency remains poorly understood. This study aims to explore the impact o...
Objective: RNA interference (RNAi) is a widely used mechanism to knock down target gene expression. Successful application of RNAi requires efficient delivery of siRNA into cells. This study demonstrates an efficient and specific knockdown of stim1, ...
Background: The role of bacterial factors in the etiology of Crohn's disease is well-documented, yet the genetic predisposition remains a subject of extensive research. Toll-like receptor 4 (TLR4) is pivotal in recognizing bacterial lipopolysaccharid...
Telomeres are critical nucleotides located at the ends of eukaryotic chromosomes, playing a vital role in maintaining genomic stability and cellular function. These structures prevent the degradation of DNA and are crucial in determining the fate of ...