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Found 8 articles for "Peking University"
Organogenesis is a critical phase of embryonic development whereby specific organs form from a relatively undifferentiated mass of cells. Our study focuses on elucidating the genetic and molecular pathways involved in lung organogenesis using zebrafi...
The development of plant organs such as leaves is a complex process orchestrated by multiple phytohormones, among which auxin plays a critical role. This study aims to investigate the influence of auxin gradient formation on leaf morphogenesis in Ara...
The intricate interplay between interhemispheric connectivity and cognitive flexibility remains a critical area of research in neuroscience. This study aims to elucidate the dynamics of neural networks involved in cognitive flexibility, with a focus ...
Protein structure prediction remains a pivotal challenge in computational biology, with significant implications for drug discovery and molecular biology. This study aims to enhance the accuracy of protein structure prediction by integrating deep lea...
The allosteric regulation of AMP-activated protein kinase (AMPK) plays a pivotal role in cellular energy homeostasis, making it a critical target for therapeutic intervention in metabolic disorders. Despite extensive study, the detailed structural me...
Understanding the mechanisms of protein folding remains a central challenge in biophysics. This study focuses on the kinetic pathways and thermodynamic stability in the folding of small globular proteins. We aimed to elucidate the interplay between f...
Gene therapy has emerged as a promising approach for the treatment of monogenic disorders, leveraging advances in genome editing technologies. This study aims to evaluate the efficacy and safety of CRISPR-Cas9 mediated gene therapy in correcting gene...
Objective: RNA interference (RNAi) is a widely used mechanism to knock down target gene expression. Successful application of RNAi requires efficient delivery of siRNA into cells. This study demonstrates an efficient and specific knockdown of stim1, ...