Vol. 20, Issue 4
Section 1
ID: VPvdn
Felix J. Müller, Priya Natarajan, Li-Yang Zhao
Keywords: Department of Cognitive Neuroscience, University of Heidelberg, Germany; Center for Brain Research, Indian Institute of Science, Bengaluru, India; Institute of Neuroscience, Peking University, China
The intricate interplay between interhemispheric connectivity and cognitive flexibility remains a critical area of research in neuroscience. This study aims to elucidate the dynamics of neural networks involved in cognitive flexibility, with a focus on the corpus callosum's role in facilitating inte...
Vol. 20, Issue 4
Section 1
ID: duMWt
Dr. Johan M. Verhoeven, Chen Li-Xia, Dr. Nneka U. Oluwaseyi
Keywords: Department of Plant Sciences, Wageningen University, Netherlands; Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, China; Department of Molecular Biology, University of Lagos, Nigeria
The burgeoning field of CRISPR-Cas9 technology provides potent tools for gene editing across various organisms, with significant implications for agricultural biotechnology. This study investigates the application of CRISPR-Cas9 to enhance abiotic stress resistance in Arabidopsis thaliana. We aimed ...
Vol. 20, Issue 4
Section 1
ID: nFTHq
Lorenz M. Fischer, Arun K. Patel, Kim Yong-Jae
Keywords: Department of Ecology, University of Freiburg, Germany; Department of Environmental Science, Indian Institute of Technology Bombay, India; School of Biological Sciences, Seoul National University, South Korea
Biodiversity conservation in temperate forests is increasingly challenged by habitat fragmentation. This study aims to quantify the impact of fragmentation on species richness and ecosystem functionality within these regions. Utilizing a combination of remote sensing data and field surveys conducted...
Vol. 20, Issue 4
Section 1
ID: sZyPg
Svenja M. Richter, Arunima N. Patel, Kenjiro Matsui
Keywords: Department of Biophysics, University of Heidelberg, Germany; Department of Chemical Engineering, Indian Institute of Technology Bombay, India; Department of Computational Biology, University of Tokyo, Japan
The process of protein folding is crucial for understanding many biological functions and dysfunctions, yet its detailed mechanisms remain elusive. This study aims to explore the kinetics of protein folding using a combination of experimental and computational techniques. We employed molecular dynam...
Vol. 20, Issue 4
Section 1
ID: RgVQ3
Sophie M. Drechsler, Tan Bo-Qiang, Ankit Kapoor
Keywords: Department of Molecular Biology, Ludwig Maximilian University of Munich, Germany; Institute of Biochemistry, Beijing University, China; Department of Biotechnology, Indian Institute of Technology Bombay, India
Understanding the intricacies of protein synthesis is crucial for advancing molecular biology and therapeutic development. This study investigates the role of ribosomal proteins in enhancing translation efficiency in eukaryotic cells. We employed a combination of ribosome profiling, quantitative pro...
Vol. 20, Issue 4
Section 1
ID: ZQTWq
Svenja Müller, Chen Ming-Hao, Aisha El-Nour
Keywords: Department of Microbial Genetics, Universität Heidelberg, Germany; Institute of Virology, Shanghai Jiao Tong University, China; Department of Molecular Biology, American University of Beirut, Lebanon
The evolutionary adaptability of viruses poses significant challenges to global health, necessitating a deeper understanding of viral evolution within host-pathogen dynamics. This study investigates the molecular mechanisms driving viral adaptation, focusing on RNA viruses known for their high mutat...
Vol. 20, Issue 4
Section 1
ID: PnCNZ
Ananya Mukherjee, Lars van der Veen, Hiroshi Nakamura
Keywords: Department of Biochemistry, University of Calcutta, Kolkata, India; Biophysical Chemistry Department, Leiden University, Leiden, Netherlands; Department of Molecular Biology, University of Tokyo, Tokyo, Japan
The sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA1a) is essential for muscle function, mediating calcium transport across the sarcoplasmic reticulum membrane. Understanding the conformational states of SERCA1a during ATP binding and hydrolysis is vital for elucidating its transport mechan...
Vol. 20, Issue 4
Section 1
ID: VHMzS
Dr. Klaus-Heinrich Bauer, Dr. Kim Soo-Jin, Dr. Alejandro Martinez-Guerrero
Keywords: Department of Developmental Biology, Ludwig Maximilian University of Munich, Germany; Department of Genetics, Seoul National University, South Korea; Department of Molecular Biology, National Autonomous University of Mexico, Mexico
The determination of cell fate during vertebrate embryogenesis is a pivotal process that dictates the developmental trajectory of the organism. This study aims to unravel the molecular and cellular mechanisms underpinning cell fate decisions in the early stages of embryonic development. We utilized ...