Vol. 19, Issue 12
2025
ID: S7Z8J
Svenja K. Müller, Rahul N. Acharya, Mingyi Zhang
Morphogenesis, the biological process that causes an organism to develop its shape, is a crucial aspect of developmental biology. This study aims to elucidate the integrative mechanisms underlying epithelial folding, a fundamental morphogenetic proce...
Vol. 19, Issue 12
2025
ID: 7YU6p
Astrid M. Fischer, Hiroshi Sugimoto, Priya N. Kumar
Organelle dynamics are critical to cellular homeostasis and adaptation to stress. This study investigates the mechanisms underlying mitochondrial redistribution in response to cellular stress in mammalian cells. We aimed to elucidate the role of cyto...
Vol. 19, Issue 12
2025
ID: 82fwa
Karl-Heinz M. Neumann, Ling Xiaofeng, Priya M. Das
The complex interplay between the MAPK and PI3K/Akt signaling pathways plays a critical role in cellular processes such as proliferation, differentiation, and survival. Despite extensive research, the precise mechanisms of crosstalk remain elusive. T...
Vol. 19, Issue 12
2025
ID: 9DnJz
Ingrid Hansen-Berg, Chukwuemeka Okafor, Sakura Yamamoto
Stem cells possess the unique ability to differentiate into various cell types, rendering them crucial for regenerative medicine. The Wnt signaling pathway is pivotal in regulating stem cell fate, though its precise role in lineage specification rema...
Vol. 19, Issue 10
2025
ID: ZuSvs
Lu Wei-Ming, Dieter H. Schneider, Priya Venkataraman
Gene therapy has emerged as a promising approach for the treatment of monogenic disorders, leveraging advances in genome editing technologies. This study aims to evaluate the efficacy and safety of CRISPR-Cas9 mediated gene therapy in correcting gene...
Vol. 19, Issue 4
2025
ID: NwR4E
Gurudeeban Selvaraj, Satyavani Kaliamurthi, Zeynep Elibol Cakmak, Turgay Cakmak
Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) is a critical enzyme found in plants and autotrophic organisms such as microalgae and cyanobacteria. This study conducts an in silico evaluation to identify RuBisCO proteins from these organis...
Vol. 18, Issue 5
2024
ID: jgqXP
Behnam Tahmasebpour, Omid Sofalian, Morteza Taghavi Sharabiani, Hasan Dehghanian
Due to the sensitivity of potatoes to viruses, the production of virus-free plants is critical for reducing production costs and enhancing yield. This study evaluates the effect of eleven combined hormonal and vitamin treatments on the main and secon...
Vol. 17, Issue 7
2023
ID: pRewW
Madhukar Saxena, Dinesh Raj Modi
Obesity is a major public health challenge of the 21st century, while type 2 diabetes mellitus (T2DM) is one of the most widespread chronic diseases globally, contributing to escalating health burdens. Both obesity and overweight status elevate the r...